ISSCR News
![New Podcast Episode. Going Out on a LIM: Rethinking the Role of LMX1A in Patterning Dopaminergic Neurons](https://images.squarespace-cdn.com/content/v1/611faaa8fee682525ee16489/1707774205407-CT59YIVIBRPEQ64IUSNM/SCR_Podcast_NewsTile_2000x1500_F.jpg)
New Podcast Episode. Going Out on a LIM: Rethinking the Role of LMX1A in Patterning Dopaminergic Neurons
This episode of The Stem Cell Report will discuss the process of directing stem cells to acquire the proper identity, an essential step in the development of effective and durable cell replacement therapies. Specifically, we will talk about the process of directing cells into a ventral mesencephalic dopaminergic fate for treating Parkinson’s disease.
![Janet Rossant Named as New Stem Cell Reports Editor-in-Chief Starting in 2025](https://images.squarespace-cdn.com/content/v1/611faaa8fee682525ee16489/1717984810221-FR78XXORK8S24CX30Q6W/JRossant.jpg)
Janet Rossant Named as New Stem Cell Reports Editor-in-Chief Starting in 2025
The International Society for Stem Cell Research (ISSCR) announces the appointment of Janet Rossant, President of the Gairdner Foundation and Senior Scientist Emeritus at the Hospital for Sick Children, Canada as the next Stem Cell Reports Editor-in-Chief beginning 1 January 2025. Dr. Rossant will take over the position held by Martin Pera, The Jackson Laboratory, USA, for nearly six years.
![New Podcast Episode. No Oligo Monopoly: Oligodendrocyte Precursor Cells in the Developing Cortex](https://images.squarespace-cdn.com/content/v1/611faaa8fee682525ee16489/1707774205407-CT59YIVIBRPEQ64IUSNM/SCR_Podcast_NewsTile_2000x1500_F.jpg)
New Podcast Episode. No Oligo Monopoly: Oligodendrocyte Precursor Cells in the Developing Cortex
Myelination is one of the last events during mammalian brain development and is thought to continue into young adulthood in humans. Even in adulthood, ongoing low-level myelination is essential for neural homeostasis, and for dynamic processes such as learning and memory. Deficits in myelination resulting in abnormal white matter and disruption of neuronal function are observed in a wide variety of disorders of the CNS. One strategy for alleviating these deficits is to enhance the genesis of myelin-forming oligodendrocytes from their upstream precursor parents, oligodendrocyte precursor cells (OPCs). However, the capability of these OPCs to contribute to remyelination in injury or disease in the adult CNS remains unclear. To better understand adult oligodendrogenesis and remyelination, our guests today characterized and compared murine OPCs during early postnatal myelination with those from adult injury-induced adult remyelination. Their findings identify two developing OPC groups subserving distinct postnatal functions and suggest that neonatal and adult OPC-mediated oligodendrogenesis are fundamentally different, The findings have important implications for therapeutic interventions aimed at myelin repair.
![The ISSCR Reduces Publishing Fees in Stem Cell Reports by 50% for First-Time Members](https://images.squarespace-cdn.com/content/v1/611faaa8fee682525ee16489/1715635301385-N73QMGXKJXQA8GBC7T5H/ISSCR+News+Thumbnail+v06-01.png)
The ISSCR Reduces Publishing Fees in Stem Cell Reports by 50% for First-Time Members
The ISSCR is pleased to offer first-time Society members a 50% reduction in author publishing costs when publishing in Stem Cell Reports, the Society’s online, open access, peer-reviewed journal.
![New in Stem Cell Reports: New Stem Cell Research May Have Implications for Liver Transplantation](https://images.squarespace-cdn.com/content/v1/611faaa8fee682525ee16489/1715194622996-S885IGBBRE1XQ7XYMTIE/AdobeStock_157180300+%281%29.jpeg)
New in Stem Cell Reports: New Stem Cell Research May Have Implications for Liver Transplantation
Research just published in the journal Stem Cell Reports, provides proof of principle that functional liver cells can be grown in a different species and could represent a solution to transplant shortage.
![](https://images.squarespace-cdn.com/content/v1/611faaa8fee682525ee16489/1e898b25-2b77-4f85-aea4-e33ef01a920e/mouse+neural+stem+cell.jpg)
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