ISSCR News


The ISSCR Forms Embryo Models Working Group
Press Release, Policy Kym Kilbourne Press Release, Policy Kym Kilbourne

The ISSCR Forms Embryo Models Working Group

Since the ISSCR released its May 2021 update to the Guidelines for Stem Cell Research and Clinical Translation, research with stem cell-based embryo models has evolved rapidly. During the extensive conversations leading up to the 2021 guidelines update, many of the embryo models that are being used today did not exist. The speed of embryo model research has resulted in new challenges for oversight committees, policymakers, funders, and journal editors grappling with how to assess the unique aspects of the science and the associated ethical and regulatory issues.

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ISSCR Holds First Academia Briefing Meeting with the European Medicines Agency
Policy Kym Kilbourne Policy Kym Kilbourne

ISSCR Holds First Academia Briefing Meeting with the European Medicines Agency

On 10 April 2024, the ISSCR held its first Academia Briefing Meeting with the European Medicines Agency (EMA). The meeting was organized by ISSCR’s Manufacturing, Clinical Translation, and Regulatory (MCTR) Committee and included invitees to present to the agency on two topics: recommendations for the manufacturing of PSC banks as starting materials for allogeneic PSC-based therapies and genetic characterization of human PSCs. Following the meeting, both parties confirmed the importance of regular meetings to ensure a bi-directional sharing of knowledge to advance the development of cellular therapies.

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New Podcast Episode. Going Out on a LIM: Rethinking the Role of LMX1A in Patterning Dopaminergic Neurons
Announcements Megan Koch Announcements Megan Koch

New Podcast Episode. Going Out on a LIM: Rethinking the Role of LMX1A in Patterning Dopaminergic Neurons

This episode of The Stem Cell Report will discuss the process of directing stem cells to acquire the proper identity, an essential step in the development of effective and durable cell replacement therapies. Specifically, we will talk about the process of directing cells into a ventral mesencephalic dopaminergic fate for treating Parkinson’s disease. 

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