| Stem Cell Science Literature Literature Highlights Archives The literature presented here is a selection of original articles, reviews and other literature highlights included each month in the ISSCR newsletter, The Pulse. The archive listings are organized by year of inclusion in the newsletter. ISSCR members can also access the literature highlights as EndNote files that can be downloaded and used as regular EndNote libraries. 2005
December 1, 2005
Book: Stem Cell Now, by Christopher T. Scott Scott, C. T. (2006). Stem Cell Now: From the Experiment That Shook the World to the New Politics of Life (New York: Pi Press). www.pipress.net A new tool for comparative genome analysis Thoughts about clinical trials Reviews Moore, P. (2005). Cell biology: ion channels and stem cells. Nature 438, 699-704. A Technology Feature by Nature Smith, A. (2005). The Battlefield of Pluripotency. Cell 123, 757-760. Introduces research by Niwa et al, 2005 Wong, M. D., Jin, Z., and Xie, T. (2005). Molecular mechanisms of germline stem cell regulation. Annu Rev Genet 39, 173-195. Papers Balazs, A. B., Fabian, A. J., Esmon, C. T., and Mulligan, R. C. (2005). Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow. Blood Nov 22 [Epub ahead of print]. Duan, Z., Zarebski, A., Montoya-Durango, D., Grimes, H. L., and Horwitz, M. (2005). Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1. Mol Cell Biol 25, 10338-10351. Hess, D. A., Wirthlin, L., Craft, T. P., Herrbrich, P. E., Hohm, S. A., Lahey, R., Eades, W. C., Creer, M. H., and Nolta, J. A. (2005). Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells. Blood Nov 3 [Epub ahead of print]. Ito, M., Liu, Y., Yang, Z., Nguyen, J., Liang, F., Morris, R. J., and Cotsarelis, G. (2005). Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med Nov 20 [Epub ahead of print]. Lavoir, M. C., Mather-Love, C., Leighton, P., Diamond, J. H., Heyer, B. S., Roberts, R., Zhu, L., Winters-Digiacinto, P., Kerchner, A., Gessaro, T., et al. (2005). High-grade transgenic somatic chimeras from chicken embryonic stem cells. Mech Dev Nov 30 [Epub ahead of print]. Matsubara, A., Iwama, A., Yamazaki, S., Furuta, C., Hirasawa, R., Morita, Y., Osawa, M., Motohashi, T., Eto, K., Ema, H., et al. (2005). Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development. J Exp Med 202, 1483-1492. Narayan, A. D., Chase, J. L., Lewis, R. L., Tian, X., Kaufman, D. S., Thomson, J. A., and Zanjani, E. D. (2005). Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. Blood Nov 8 [Epub ahead of print]. Niwa, H., Toyooka, Y., Shimosato, D., Strumpf, D., Takahashi, K., Yagi, R., and Rossant, J. (2005). Interaction between Oct3/4 and Cdx2 Determines Trophectoderm Differentiation. Cell 123, 917-929. Xi, R., and Xie, T. (2005). Stem cell self-renewal controlled by chromatin remodeling factors. Science 310, 1487-1489. Yilmaz, O. H., Kiel, M. J., and Morrison, S. J. (2005). SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood Oct 11 [Epub ahead of print]. Yu, H., Yuan, Y., Shen, H., and Cheng, T. (2005). Hematopoietic stem cell exhaustion impacted by p18INK4C and p21Cip1/Waf1 in opposite manners. Blood Oct 18 [Epub ahead of print]. Zvetkova, I., Apedaile, A., Ramsahoye, B., Mermoud, J. E., Crompton, L. A., John, R., Feil, R., and Brockdorff, N. (2005). Global hypomethylation of the genome in XX embryonic stem cells. Nat Genet 37, 1274-1279.
November 1, 2005
Journal News: Shattil, S. J. (2005). Springtime for stem cells. Blood 106, 2935. The HapMap Project: The International HapMap Consortium is cataloging the common patterns of human DNA sequence variation, a tool that is hoped will accelerate the identification of genetic factors that influence medical traits. The first phase of the project is reported: Official Report of the International HapMap Consortium "News and Views" Review A demonstration of functionality Perspectives Reviews Dubois-Dalcq, M., Ffrench-Constant, C., and Franklin, R. J. (2005). Enhancing central nervous system remyelination in multiple sclerosis. Neuron 48, 9-12. Guasch, G., and Fuchs, E. (2005). Mice in the world of stem cell biology. Nat Genet 37, 1201-1206. Li, L., and Xie, T. (2005). Stem Cell Niche: Structure and Function. Annu Rev Cell Dev Biol 21, 605-631. Mishra, L., Derynck, R., and Mishra, B. (2005). Transforming growth factor-beta signaling in stem cells and cancer. Science 310, 68-71. Wagers, A. J., and Conboy, I. M. (2005). Cellular and molecular signatures of muscle regeneration: current concepts and controversies in adult myoge October 1, 2005
ETHICS & POLICIES ARTICLES: Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, Young RA (2005). Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122:947 Chang YJ, Shih DT, Tseng CP, Hsieh TB, Lee DC, Hwang SM (2005). Disparate Mesenchyme-Lineage Tendencies in Mesenchymal Stem Cells from Human Bone Marrow and Umbilical Cord Blood. Stem Cells Sep 22 [Epub ahead of print] Klein C, Butt SJ, Machold RP, Johnson JE, Fishell G (2005). Cerebellum- and forebrain-derived stem cells possess intrinsic regional character. Development 132:4497. Osada T, Tamamaki N, Song SY, Kakazu N, Yamazaki Y, Makino H, Sasaki A, Hirayama T, Hamada S, Nave KA, Yanagimachi R, Yagi T (2005). Developmental pluripotency of the nuclei of neurons in the cerebral cortex of juvenile mice.J Neurosci 25:8368. Rosu-Myles M, Stewart E, Trowbridge J, Ito CY, Zandstra P, Bhatia M (2005). A unique population of bone marrow cells migrates to skeletal muscle via hepatocyte growth factor/c-met axis. J Cell Sci 118:4343. Sarmento LM, Huang H, Limon A, Gordon W, Fernandes J, Tavares MJ, Miele L, Cardoso AA, Classon M, Carlesso N (2005). Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation. J Exp Med 202:157. Sun YM, Greenway DJ, Johnson R, Street M, Belyaev ND, Deuchars J, Bee T, Wilde S, Buckley NJ (2005). Distinct Profiles of REST Interactions with Its Target Genes at Different Stages of Neuronal Development. Mol Biol Cell Sep 29 [Epub ahead of print] Tada S, Era T, Furusawa C, Sakurai H, Nishikawa S, Kinoshita M, Nakao K, Chiba T, Nishikawa S (2005). Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture. Development 132:4363. Taranger CK, Noer A, Sorensen AL, Hakelien AM, Boquest AC, Collas P (2005). Induction of Dedifferentiation, Genome-wide Transcriptional Programming, and Epigenetic Reprogramming by Extracts of Carcinoma and Embryonic Stem Cells. Mol Biol Cell Sep 29 [Epub ahead of print]
September 2, 2005
September 1, 2005
July 1, 2005
Kiel MJ, Yilmaz ÖH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ (2005). SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells. Cell 121:1109. ETHICS AND POLICY: Devolder K (2005). Creating and sacrificing embryos for stem cells. J Med Ethics 31:366 NEW CELL LINES: Findikli N, Kahraman S, Akcin O, Sertyel S, Candan Z (2005). Establishment and characterization of new human embryonic stem cell lines. Reprod Biomed Online 10:617. Chen H, Qian K, Hu J, Liu D, Lu W, Yang Y, Wang D, Yan H, Zhang S, Zhu G (2005). The derivation of two additional human embryonic stem cell lines from day 3 embryos with low morphological scores. Hum Reprod. Jun 9; [Epub ahead of print] CANCER & STEM CELLS: Tai MH, Chang CC, Olson LK, Trosko JE (2005). Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis 26:495. METHODS: Mothe AJ, Kulbatski I, van Bendegem RL, Lee L, Kobayashi E, Keating A, Tator CH (2005). Analysis of Green Fluorescent Protein Expression in Transgenic Rats for Tracking Transplanted Neural Stem/Progenitor Cells. J Histochem Cytochem Jun 27; [Epub ahead of print].Tesar PJ (2005). Derivation of germ-line-competent embryonic stem cell lines from preblastocyst mouse embryos. Proc Natl Acad Sci U S A May 25; [Epub ahead of print] Scheel JR, Ray J, Gage FH, Barlow C (2005). Quantitative analysis of gene expression in living adult neural stem cells by gene trapping. Nat Methods 2:363. Zheng GD, Hidaka K, Morisaki T (2005). Stable and uniform gene suppression by site-specific integration of siRNA expression cassette in murine embryonic stem cells. Stem Cells Jun 7; [Epub ahead of print] REVIEW: Hoffman LM, Carpenter MK (2005). Characterization and culture of human embryonic stem cells. Nat Biotechnol 23:699. Special issue of Experimental Cell Research dedicated to reviews on stem cells: Back to top
June 1, 2005
PAPER OF THE YEAR: Hwang WS, Roh SI, Lee BC, Kang SK, Kwon DK, Kim S, Kim SJ, Park SW, Kwon HS, Lee CK, Lee JB, Kim JM, Ahn C, Paek SH, Chang SS, Koo JJ, Yoon HS, Hwang JH, Hwang YY, Park YS, Oh SK, Kim HS, Park JH, Moon SY, Schatten G (2005). Patient-Specific Embryonic Stem Cells Derived from Human SCNT Blastocysts. Science May 19; [Epub ahead of print] METHODS:McKenzie JL, Gan OI, Doedens M, Dick JE (2005). Short-term repopulating stem cells are efficiently detected following intra-femoral transplantation into NOD/SCID recipients depleted of CD122+ cells. Blood May 5 [Epub ahead of print] Ng ES, Davis RP, Azzola L, Stanley EG, Elefanty AG (2005).Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation. Blood 24 May [Epub ahead of print] Pelz O, Wu M, Nikolova T, Kamprad M, Ackermann M, Egger D, Emmrich F, Wobus AM, Cross M (2005). Duplex polymerase chain reaction quantification of human cells in a murine background. Stem Cells 23:828. Qin M, Tai G, Collas P, Polak JM, Bishop AE (2005). Cell extract-derived differentiation of embryonic stem cells. Stem Cells. 2005 Jun;23(6):712-8. Stojkovic P, Lako M, Przyborski S, Stewart R, Armstrong L, Evans J, Zhang X, Stojkovic M (2005). Human-serum matrix supports undifferentiated growth of human embryonic stem cells. Stem Cells May 11 [Epub ahead of print] ARTICLES: Amit M, Winkler ME, Menke S, Bruning E, Buscher K, Denner J, Haverich A, Itskovitz-Eldor J, Martin U 2005). No evidence for infection of human embryonic stem cells by feeder cell-derived murine leukemia viruses. Stem Cells 23:761. Deasy BM, Gharaibeh BM, Pollett JB, Jones MM, Lucas MA, Kanda Y, Huard J (2005). Long-Term Self-Renewal of Postnatal Muscle-derived Stem Cells. Mol Biol Cell May 4; [Epub ahead of print] Grey C, Mery A, Puceat M (2005). Fine-tuning in Ca2+ homeostasis underlies progression of cardiomyopathy in myocytes derived from genetically modified embryonic stem cells. Hum Mol Genet 14:1367.
Hjerling-Leffler J, Marmigere F, Heglind M, Cederberg A, Koltzenburg M, Enerback S, Ernfors P (2005). The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes. Development 132:2623. Ioannidis P, Mahaira LG, Perez SA, Gritzapis AD, Sotiropoulou PA, Kavalakis GJ, Antsaklis AI, Baxevanis CN, Papamichail M (2005). CRD-BP/IMP1 expression characterizes cord blood CD34+ stem cells and affects c-myc and IGF-II expression in MCF-7 cancer cells. J Biol Chem 280:20086.
Kania G, Corbeil D, Fuchs J, Tarasov KV, Blyszczuk P, Huttner WB, Boheler KR, Wobus AM (2005). Somatic Stem Cell Marker Prominin-1/CD133 Is Expressed in Embryonic Stem Cell-Derived Progenitors. Stem Cells 23:791. Kawamura T, Ono K, Morimoto T, Wada H, Hirai M, Hidaka K, Morisaki T, Heike T, Nakahata T, Kita T, Hasegawa K (2005). Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes. J Biol Chem 280:19682. Kofidis T, de Bruin JL, Yamane T, Tanaka M, Lebl DR, Swijnenburg RJ, Weissman IL, Robbins RC (2005). Stimulation of paracrine pathways with growth factors enhances embryonic stem cell engraftment and host-specific differentiation in the heart after ischemic myocardial injury. Circulation 111:2486. Kotton DN, Fabian AJ, Mulligan RC (2005). A novel stem cell population in adult liver with potent hematopoietic reconstitution activity. Blood May 3 [Epub ahead of print] Kratchmarova I, Blagoev B, Haack-Sorensen M, Kassem M, Mann M (2005). Mechanism of Divergent Growth Factor Effects in Mesenchymal Stem Cell Differentiation. Science 308:1472. Kustikova O, Fehse B, Modlich U, Yang M, Dullmann J, Kamino K, von Neuhoff N, Schlegelberger B, Li Z, Baum C (2005). Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking. Science 308:1171. Kucia M, Reca R, Miekus K, Wanzeck J, Wojakowski W, Janowska-Wieczorek A, Ratajczak J, Ratajczak MZ (2005). Trafficking of Normal Stem Cells and Metastasis of Cancer Stem Cells Involve Similar Mechanisms: Pivotal Role of the SDF-1-CXCR4 Axis. Stem Cells May 11 [Epub ahead of print] Paek HJ, Moise LJ, Morgan JR, Lysaght MJ (2005). Sequestration and Synthesis: The Source of Insulin in Cell Clusters Differentiated from Murine Embryonic Stem Cells. Stem Cells May 11; [Epub ahead of print]
June 1, 2005
Rugg-Gunn PJ, Ferguson-Smith AC, Pedersen RA (2005). Epigenetic status of human embryonic stem cells. Nat Genet 37:585. Stier S, Ko Y, Forkert R, Lutz C, Neuhaus T, Grunewald E, Cheng T, Dombkowski D, Calvi LM, Rittling SR, Scadden DT (2005). Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med May 31 [Epub ahead of print] Rodriguez AM, Pisani D, Dechesne CA, Turc-Carel C, Kurzenne JY, Wdziekonski B, Villageois A, Bagnis C, Breittmayer JP, Groux H, Ailhaud G, Dani C (2005). Transplantation of a multipotent cell population from human adipose tissue induces dystrophin expression in the immunocompetent mdx mouse. J Exp Med 201:1397. Wang L, Menendez P, Shojaei F, Li L, Mazurier F, Dick JE, Cerdan C, Levac K, Bhatia M (2005). Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J Exp Med 201:1603. Wehman AM, Staub W, Meyers JR, Raymond PA, Baier H (2005). Genetic dissection of the zebrafish retinal stem-cell compartment. Dev Biol 281:53. Yuasa H, Oike Y, Iwama A, Nishikata I, Sugiyama D, Perkins A, Mucenski ML, Suda T, Morishita K (2005). Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression. EMBO J May 12 [Epub ahead of print]
May 1, 2005
POLICY: Guenin LM (2005). Stem cells, cloning, and regulation. Mayo Clinic Proc. 80:241. STEM CELLS & CANCER: Bapat SA, Mali AM, Koppikar CB, Kurrey NK (2005). Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer. Cancer Res 65:3025. Burns JS, Abdallah BM, Guldberg P, Rygaard J, Schroder HD, Kassem M (2005). Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mesenchymal stem cells. Cancer Res 65:3126. Nakamizo A, Marini F, Amano T, Khan A, Studeny M, Gumin J, Chen J, Hentschel S, Vecil G, Dembinski J, Andreeff M, Lang FF (2005). Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res 65:3307. Rubio D, Javier Garcia-Castro J, Martin MC, de la Fuente R, Cigudosa JC, Lloyd AC, Bernad A (2005). Spontaneous Human Adult Stem Cell Transformation. Cancer Res 65:3035. REVIEWS: Alex Gregorieff A and Hans Clevers H (2005). Wnt signaling in the intestinal epithelium: from endoderm to cancer. Genes Dev 19:877. Chen EH, Olson EN (2005). Unveiling the mechanisms of cell-cell fusion. Science 308:369. METHODS: Zhang SO, Weisblat DA (2005). Applications of mRNA injections for analyzing cell lineage and asymmetric cell divisions during segmentation in the leech Helobdella robusta. Development 2005 Mar 23 [Epub ahead of print] ARTICLES: Armstrong L, Saretzki G, Peters H, Wappler I, Evans J, Hole N, von Zglinicki T, Lako M (2005). Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage. Stem Cells 23:516. Gros J, Manceau M, Thome V, Marcelle C (2005). A common somitic origin for embryonic muscle progenitors and satellite cells. Nature. 2005 Apr 20 [Epub ahead of print] Jones NC, Tyner KJ, Nibarger L, Stanley HM, Cornelison DD, Fedorov YV, Olwin BB (2005). The p38{alpha}/{beta} MAPK functions as a molecular switch to activate the quiescent satellite cell. J Cell Biol 169:105. Kleber M, Lee H-Y, Wurdak H, Buchstaller J, Riccomagno MM, Ittner LM, Suter U, Epstein DJ, Sommer L (2005). Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. J Cell Biol, 18 April [Epub ahead of print] Martinez-Ceballos E, Chambon P, Gudas LJ (2005). Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or LIF removal. J Biol Chem 280:16484. Zambidis ET, Peault B, Park TS, Bunz F, Civin CI (2005). Hematopoietic differentiation of human embryonic stem cells progresses through sequential hemato-endothelial, primitive, and definitive stages resembling human yolk sac development. Blood, 14 April [Epub ahead of print]
April 1, 2005
REVIEWS: Radtke F, Clevers H (2005). Self-renewal and cancer of the gut: two sides of a coin. Science 307:1904. METHODS: Wang L, Li L, Menendez P, Cerdan C, Bhatia M (2005). Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development. Blood Feb 17; [Epub ahead of print] BOOKS: The Proteomics Protocols Handbook ARTICLES: Holmberg J, Armulik A, Senti KA, Edoff K, Spalding K, Momma S, Cassidy R,Flanagan JG, Frisen J (2005). Ephrin-A2 reverse signaling negatively regulates neural progenitor proliferation and neurogenesis. Genes Dev 19:462. Opferman JT, Iwasaki H, Ong CC, Suh H, Mizuno S, Akashi K, Korsmeyer SJ (2005). Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells. Science 307:1101. Plusa B, Hadjantonakis AK, Gray D, Piotrowska-Nitsche K, Jedrusik A, Stojkovic P, Lako M, Stewart R, Przyborski S, Armstrong L, Evans J, Murdoch A, Strachan T, Stojkovic M (2005).
March 1, 2005
The September 20 issue of Oncogene is a review issue dedicated to "Stem Cells: Growth and Cancer" REVIEWS: Hsieh J, Gage FH (2004). Epigenetic control of neural stem cell fate. Curr Opin Genet Dev 14:461. BOOKS: Cell Cycle Control: Mechanisms and Protocols METHODS: Smits E, Ponsaerts P, Lenjou M, Nijs G, Van Bockstaele DR, Berneman ZN, Van Tendeloo VF (2004). RNA-based gene transfer for adult stem cells and T cells. Leukemia 18:1898. ARTICLES: Blelloch RH, Hochedlinger K, Yamada Y, Brennan C, Kim M, Mintz B, Chin L, Jaenisch R(2004). Nuclear cloning of embryonal carcinoma cells. Proc Natl Acad Sci U S A. 101:13985. Hansson M, Tonning A, Frandsen U, Petri A, Rajagopal J, Englund MC, Heller RS, Hakansson J, Fleckner J, Skold HN, Melton D, Semb H, Serup P (2004). Artifactual insulin release from differentiated embryonic stem cells. Diabetes 53:2603. He XC, Zhang J, Tong WG, Tawfik O, Ross J, Scoville DH, Tian Q, Zeng X, He X, Wiedemann LM, Mishina Y, Li L(2004). BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet 36:1117. Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, Goodell MA, Brenner MK (2004). A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci U S A 101:14228. Matsuoka Y, Kubota H, Adachi E, Nagai N, Marutani T, Hosokawa N, Nagata K (2004). Insufficient folding of type IV collagen and formation of abnormal basement membrane-like structure in embryoid bodies derived from Hsp47-null embryonic stem cells. Mol Biol Cell 15:4467 Messina E, De Angelis L, Frati G, Morrone S, Chimenti S, Fiordaliso F, Salio M, Battaglia M,
2004
October 5, 2004
The September issue of ONCOGENE is dedicated to stem cells. And the discussion goes on.... Otani A, Dorrell MI, Kinder K, Moreno SK, Nusinowitz S, Banin E, Heckenlively J, Friedlander M (2004). Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells. J Clin Invest 114:765. The Answer? Kawada, H., Fujita, J., Kinjo, K., Matsuzaki, Y., Tsuma, M., Miyatake, H., Muguruma, Y., Tsuboi, K., Itabashi, Y., Ikeda, Y. , et al. (2004). Non-hematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction. Blood, Aug 5 [Epub ahead of print] PAPER OF THE MONTH: A novel method that could be adapted to other proteins and systems: BOOKS: The Proteus Effect: Stem Cells and their Promise for Medicine Methods in Molecular Biology: Basic Cell Culture Protocols Methods in Molecular Biology: Epigenetic Protocols Editor: O.T. Tollefsbol Second Edition, Vol. 287, Humana Press, 2004 REVIEWS: Aicher A, Heeschen C, Dimmeler S (2004). The role of NOS3 in stem cell mobilization. Trends Mol Med 10:421. Moon RT, Kohn AD, De Ferrari GV, Kaykas A (2004). WNT and beta-catenin signalling: diseases and therapies. Nat Rev Genet 5:691. METHODS: Orner BP, Derda R, Lewis RL, Thomson JA, Kiessling LL (2004). Arrays for the combinatorial exploration of cell adhesion. J Am Chem
September 8, 2004
New Cell Line: Stojkovic M, Lako M, Stojkovic P, Stewart R, Przyborski S, Armstrong L, Evans J, Herbert M, Hyslop L, Ahmad S, Murdoch A, Strachan T (2004). Derivation of human embryonic stem cells from day-8 blastocysts recovered after three-step in vitro culture. Stem Cells 22:790. Reviews: Moon RT, Kohn AD, De Ferrari GV, Kaykas A (2004). Wnt and ß-Catenin Signalling: Diseases and Therapies. Nature Reviews Genetics 5: 691. Stojkovic M, Lako M, Strachan T, Murdoch A (2004). Derivation, growth and applications of human embryonic stem cells. Reproduction 128:259. Ethics: Karpowicz P, Cohen CB, van der Kooy D (2004). It is ethical to transplant human stem cells into nonhuman embryos. Nat Med 10:331. Walters L (2004). Human embryonic stem cell research: An intercultural perspective. Kennedy Institute of Ethics Journal 14:3. Methods: Matin MM, Walsh JR, Gokhale PJ, Draper JS, Bahrami AR, Morton I, Moore HD, Andrews PW (2004). Specific Knockdown of Oct4 and {beta}2-microglobulin Expression by RNA Interference in Human Embryonic Stem Cells and Embryonic Carcinoma Cells. Stem Cells 22:659. Articles: Blanpain C, Lowry WE, Geoghegan A, Polak L, Fuchs E (2004). Self-Renewal, Multipotency, and the Existence of Two Cell Populations within an Epithelial Stem Cell Niche. Cell 118:635. Besser D (2004). Expression of Nodal, Lefty-A, and Lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3. J Biol Chem Aug 11 [Epub ahead of print] Blelloch RH, Hochedlinger K, Yamada Y, Brennan C, Kim M, Mintz B, Chin L, Jaenisch R (2004). Nuclear cloning of embryonal carcinoma cells. Proc Natl Acad Sci U S A. Aug 11 [Epub ahead of print] Christopherson KW 2nd, Hangoc G, Mantel CR, Broxmeyer HE (2004). Modulation of hematopoietic stem cell homing and engraftment by CD26. Science 305:1000. Daheron L, Opitz SL, Zaehres H, Lensch WM, Andrews PW, Itskovitz-Eldor J, Daley GQ (2004). LIF/STAT3 Signaling Fails to Maintain Self-Renewal of Human Embryonic StemCells. Stem Cells 22:770. Sumi T, Fujimoto Y, Nakatsuji N,
August 3, 2004
Special Stem Cell Issue: July 10 issue of Lancet New Line: Paper of the Month: Ethics: Discussion: Khosrotehrani K. Johnson KL, Cha DH, Salomon RN, Bianchi DW (2004). Transfer of Fetal Cells With Multilineage Potential to Maternal Tissue. JAMA 292:75. Taylor HS (2004). Endometrial cells derived from donor stem cells in bone marrow transplant recipients. JAMA 292:81. Wurmser AE, Nakashima K, Summers RG, Toni N, D'Amour KA, Lie DC, Gage FH (2004). Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature 430:350. Reviews: Pittenger MF, Martin BJ (2004). Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res 95:9. Techniques: Xu L, O'Malley T, Sands MS, Wang B, Meyerrose T, Haskins ME, Ponder KP (2004).
July 7, 2004
PICK OF THE MONTH Xie H, Ye M, Feng R, Graf T (2004). Stepwise reprogramming of B cells into macrophages. Cell 117:663. GENERAL Kamakura S, Oishi K, Yoshimatsu T, Nakafuku M, Masuyama N, Gotoh Y (2004). Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nat Cell Biol 6:547.DISCUSSION Camargo FD, Finegold M, Goodell MA (2004). Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners. J Clin Invest 113:1266. Willenbring H, Bailey AS, Foster M, Akkari Y, Dorrell C, Olson S, Finegold M, Fleming WH, Grompe M (2004). Myelomonocytic cells are sufficient for therapeutic cell fusion in liver. Nat Med. 2004 Jun 13 [Epub ahead of print] Harris RG, Herzog EL, Bruscia EM, Grove JE, Van Arnam JS, Krause DS (2004). Lack of a fusion requirement for development of bone marrow-derived epithelia. Science 305:90. Jang YY, Collector MI, Baylin SB, Diehl AM, Sharkis SJ (2004). Hematopoietic stem cells convert into liver cells within days without fusion. Nat Cell Biol 6:532. REVIEWS Snyder EY, Daley GQ, Goodell M (2004). Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system. J Neurosci Res 76:157. Trounson A (2004). Stem cells, plasticity and cancer - uncomfortable bed fellows. Development 131:2763. Losordo DW, Dimmeler S (2004). Therapeutic angiogenesis and vasculogenesis for ischemic disease: part II: cell-based therapies. Circulation 109:2692.METHODS Anderson DG, Levenberg S, Langer R (2004). Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells. Nat Biotechnol 22:863. Guo G, Wang W, Bradley A (2004). Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells. Nature 429:891. Notingher I, Bisson I, Bishop AE, Randle WL, Polak JM, Hench LL (2004). In situ spectral monitoring of mRNA translation in embryonic stem cells during differentiation in vitro. Anal Chem 76:3185. PRIMARY ARTICLES: Buaas FW, Kirsh AL, Sharma M, McLean DJ, Morris JL, Griswold MD, de Rooij DG, Braun RE (2004). Plzf is required in adult male germ cells for stem cell self-renewal. Nat Genet 36:647. Costoya JA, Hobbs RM, Barna M, Cattoretti G, Manova K, Sukhwani M, Orwig KE, Wolgemuth DJ, Pandolfi PP (2004). Essential role of Plzf in maintenance of spermatogonial stem cells. Nat Genet 36(6):653. Carr AR, Choksi SP, Brand AH (2004). Turning back the clock on neural progenitors. Bioessays 26:711. Campos LS, Leone DP, Relvas JB, Brakebusch C, Fassler R, Suter U, Ffrench-Constant C (2004). {beta}1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance. Development 131:3433. Garcion E, Halilagic A, Faissner A, Ffrench-Constant C (2004). Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C. Development 131:3423. Hope KJ, Jin L, Dick JE (2004). Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity. Nat Immunol May 30 [Epub ahead of print] Shen Q, Goderie SK, Jin L, Karanth N, Sun Y, Abramova N, Vincent P, Pumiglia K, Temple S (2004). Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science 304:1338. Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS, Moon SY, Kim VN, Kim KS (2004). Human embryonic stem cells express a unique set of microRNAs. Dev Biol 270:488.
June 1, 2004
New Human ES Cell Lines: Kakoki M, Tsai YS, Kim HS, Hatada S, Ciavatta DJ, Takahashi N, Arnold LW,Maeda N, Smithies O (2004). Altering the expression in mice of genes by modifying their 3' regions. Dev Cell 6:597. Kiriakidou M, Nelson PT, Kouranov A, Fitziev P, Bouyioukos C, Mourelatos Z, Hatzigeorgiou A (2004). A combined computational-experimental approach predicts human microRNA targets. Genes Dev 18:1165. Navarro C, Puthalakath H, Adams JM, Strasser A, Lehmann R (2004). Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate. Nat Cell Biol 6:427. Reviews: De Bruijn MF, Speck NA (2004). Core-binding factors in hematopoiesis and immune function. Oncogene 23:4238. Techniques: Primary Articles: Brawley C, Matunis E (2004). Regeneration of Male Germline Stem Cells by Spermatogonial Dedifferentiation In Vivo. Science May 13 [Epub ahead of print] Brunelli S, Tagliafico E, De Angelis FG, Tonlorenzi R, Baesso S, Ferrari S, Niinobe M, Yoshikawa K, Schwartz RJ, Bozzoni I, Ferrari S, Cossu G (2004).
May 4, 2004
REVIEW ARTICLES: Al-Hajj M, Becker MW, Wicha M, Weissman I, Clarke MF (2004). Therapeutic implications of cancer stem cells. Curr Opin Genet Dev 14:43. Davila JC, Cezar GG, Thiede M, Strom S, Miki T, Trosko J (2004). Use and Application of Stem Cells in Toxicology. Toxicol Sci. 2004 Mar 10 [Epub ahead of print] Snyder EY, Daley GQ, Goodell M (2004). Taking stock and planning for the next decade: Realistic prospects for stem cell therapies for the nervous system. J Neurosci Res 76:157. PRIMARY ARTICLES: Bhattacharya B, Miura T, Brandenberger R, Mejido J, Luo Y, Yang AX, Joshi BH, Ginis I, Thies RS, Amit M, Lyons I, Condie BG, Itskovitz-Eldor J, Rao MS, Puri RK (2004). Gene expression in human embryonic stem cell lines: unique molecular signature. Blood 103:2956. Buzzard JJ, Gough NM, Crook JM, Colman A (2004). Karyotype of human ES cells during extended culture. Nat Biotechnol 22:381. Andrews PW (2004). Response: Karyotype of human ES cells during extended culture. Nat Biotechnol 22:382. Ginis I, Luo Y, Miura T, Thies S, Brandenberger R, Gerecht-Nir S, Amit M, Hoke A, Carpenter MK, Itskovitz-Eldor J, Rao MS (2004). Differences between human and mouse embryonic stem cells. Dev Biol 269:360. Iwatani H, Ito T, Imai E, Matsuzaki Y, Suzuki A, Yamato M, Okabe M, Hori M (2004). Hematopoietic and nonhematopoietic potentials of Hoechst/side population cells isolated from adult rat kidney. Kidney Int 65:1604. Yuan Y, Shen H, Franklin DS, Scadden DT, Cheng T (2004).In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat Cell Biol 6:436.
Kha HT, Basseri B, Shouhed D, Richardson J, Tetradis S, Hahn TJ, Parhami F (2004).Oxysterols regulate differentiation of mesenchymal stem cells: pro-bone and anti-fat. J Bone Miner Res 19:830.
April 6, 2004
Balsam LB, Wagers AJ, Christensen JL, Kofidis T, Weissman IL, Robbins RC (2004). Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature Mar 21 [Epub ahead of print]
Murry CE, Soonpaa MH, Reinecke H, Nakajima H, Nakajima HO, Rubart M, Pasumarthi KB, Ismail Virag J, Bartelmez SH, Poppa V, Bradford G, Dowell JD, Williams DA, Field LJ (2004). Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature Mar 21 [Epub ahead of print]
Schmitt TM, De Pooter RF, Gronski MA, Cho SK, Ohashi PS, Zuniga-Pflucker JC (2004). Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro. Nat Immunol. 2004 Apr;5(4):410-7. GENERAL INTEREST: Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, Weinrauch Y, Zychlinsky A (2004). Neutrophil extracellular traps kill bacteria. Science 303:1532.
METHODS: Jackson KA, Snyder DS, Goodell MA (2004). Skeletal muscle fiber-specific green autofluorescence: potential for stem cell engraftment artifacts. Stem Cells 22:180. Janicki SM, Tsukamoto T, Salghetti SE, Tansey WP, Sachidanandam R, Prasanth KV, Ried T, Shav-Tal Y, Bertrand E, Singer RH, Spector DL (2004). From silencing to gene expression: real-time analysis in single cells. Cell 116:683. Schomber T, Kalberer CP, Wodnar-Filipowicz A, Skoda RC (2004). Gene silencing by lentivirus-mediated delivery of siRNA in human CD34+ cells. Blood Feb 26 [Epub ahead of print] REVIEW ARTICLES: Drukker M, Benvenisty N (2004). The immunogenicity of human embryonic stem-derived cells. Trends Biotechnol 22:136. Wagers AJ, Weissman IL (2004). Plasticity of adult stem cells. Cell 116:639. PRIMARY ARTICLES: Burt RK, Verda L, Kim DA, Oyama Y, Luo K, Link C (2004). Embryonic Stem Cells As an Alternate Marrow Donor Source: Engraftment without Graft-Versus-Host Disease. J. Exp. Med. published 29 March 2004, 10.1084/jem.20031916 Eggan K, Baldwin K, Tackett M, Osborne J, Gogos J, Chess A, Axel
March 1, 2004
Papers of the Month: Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmeyer J, Zucker JP, Wang S, Morton CC, McMahon AP, Powers D, Melton DA (2004). Derivation of Embryonic Stem-Cell Lines from Human Blastoscycts. N Engl J Med March 25 issue. Sen G, Wehrman TS, Myers JW, Blau HM (2004). Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nat Genet 36:183. Methods: Amit M, Shariki C, Margulets V, Itskovitz-Eldor J (2004). Feeder and Serum-Free Culture of Human Embryonic Stem Cells. Biol Reprod 70:837 Fritsch L, Martinez LA, Sekhri R, Naguibneva I, Gerard M, Vandromme M, Articles: Abeyta MJ, Clark AT, Rodriguez RT, Bodnar MS, Pera RA, Firpo MT (2004).Unique Gene Expression Signatures Of Independently-Derived Human Embryonic Stem Cell Lines. Hum Mol Genet 13:601. Brun AC, Bjornsson JM, Magnusson M, Larsson N, Leveen P, Ehinger M, Nilsson E, Karlsson S (2004). Hoxb4 deficient mice have normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells. Blood Feb 12 [Epub ahead of print] Chamberlain JR, Schwarze U, Wang PR, Hirata RK, Hankenson KD, Pace JM, Underwood RA, Song KM, Sussman M, Byers PH, Russell DW (2004). Gene targeting in stem cells from individuals with osteogenesis imperfecta. Science 303:1198. Hisa T, Spence SE, Rachel RA, Fujita M, Nakamura T, Ward JM, Devor-Henneman DE, Saiki Y, Kutsuna H, Tessarollo L, Jenkins NA, Copeland NG (2004). Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. EMBO J 23:450. Kawase E, Wong MD, Ding BC, Xie T (2004). Gbb/Bmp signaling is essential for maintaining germline stem cells and for repressing bam transcription in the Drosophila testis. Development Feb 18 [Epub ahead of print] Song X, Wong MD, Kawase E, Xi R, Ding BC, McCarthy JJ, Xie T (2004). Lanza R, Moore MA, Wakayama T, Perry AC, Shieh JH, Hendrikx J, Leri A, Lu SJ, Li F, Vida L, Honig GR (2004). Mak W, Nesterova TB, de Napoles M, Appanah R, Yamanaka S, Otte AP, Brockdorff N (2004). Reactivation of the paternal X chromosome in early mouse embryos. Science 303:666. Okamoto I, Otte AP, Allis CD, Reinberg D, Heard E (2004). Epigenetic dynamics of imprinted x inactivation during early mouse development. Science. 2004 303:644. Nobuhisa I, Kato R, Inoue H, Takizawa M, Okita K, Yoshimura A, Taga T (2004). Spred-2 Suppresses Aorta-Gonad-Mesonephros Hematopoiesis by Inhibiting MAP Kinase Activation. J Exp Med Feb 23 [Epub ahead of print] Sipione S, Eshpeter A, Lyon JG, Korbutt GS, Bleackley RC (2004). Insulin expressing cells from differentiated embryonic stem cells are not beta cells. Diabetologia Feb 14 [Epub ahead of print] Wang Z, Lin H (2004). Nanos Maintains Germline Stem Cell Self-Renewal by Preventing Differentiation. Science Feb 19 [Epub ahead of print]
February 4, 2004
PAPER OF THE MONTH Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M, Fuchs E (2004). Defining the epithelial stem cell niche in skin. Science 303:359 METHODS Bryder D, Sasaki Y, Borge OJ, and Jacobsen S-E W (2004). Deceptive Multilineage Reconstitution Analysis of Mice Transplanted with Hemopoietic Stem Cells, and Implications for Assessment of Stem Cell Numbers and Lineage Potentials. J Immunol 172:1548. Kato Y, Imabayashi H, Mori T, Tani T, Taniguchi M, Higashi M, Matsumoto M, Umezawa A, Tsunoda Y (2004). Nuclear Transfer of Adult Bone Marrow Mesenchymal Stem Cells: Developmental Totipotency of Tissue-Specific Stem Cells from an Adult Mammal. Biol Reprod 70:415. ARTICLES Curtis DJ, Hall MA, Van Stekelenburg LJ, Robb L, Jane SM, Begley CG (2004). SCL is required for normal function of short-term repopulating hematopoietic stem cells. Blood Jan 15 [Epub ahead of print] Kunisato A, Chiba S, Saito T, Kumano K, Nakagami-Yamaguchi E, Yamaguchi T, Hirai H (2004). Stem cell leukemia (SCL) directs hematopoietic stem cell fate. Blood Jan 15 [Epub ahead of print] Langer JC, Henckaerts E, Orenstein J, Snoeck H-W (2004). Quantitative Trait Analysis Reveals Transforming Growth Factor-{beta}2 as a Positive Regulator of Early Hematopoietic Progenitor and Stem Cell Function. J Exp Med 199:5. Martinho RG, Kunwar PS, Casanova J, Lehmann R (2004). A noncoding RNA Is Required for the Repression of RNApolII-Dependent Transcription in Primordial Germ Cells. Current Biology 14:159.
January 20, 2004
GENERAL INTEREST Schneider R, Bannister AJ, Myers FA, Thorne AW, Crane-Robinson C, Kouzarides T (2004). Histone H3 lysine 4 methylation patterns in higher eukaryotic genes. Nat Cell Biol 6:73. RESOURCE Pohar TT, Sun H, Davuluri RV(2004). HemoPDB: Hematopoiesis Promoter Database, an information resource of transcriptional regulation in blood cell development. Nucleic Acids Res 32:D86. METHODS Psarras S, Karagianni N, Kellendonk C, Tronche F, Cosset FL, Stocking C, Schirrmacher V, Boehmer Hv H, Khazaie K (2004). Gene transfer and genetic modification of embryonic stem cells by Cre- and Cre-PR-expressing MESV-based retroviral vectors. J Gene Med 6:32. Tao W, Hangoc G, Cooper S, Broxmeyer HE (2004). SDF-1alpha/CXCL12 enhances retroviral-mediated gene transfer into immature subsets of human and murine hematopoietic progenitor cells. Gene Ther 11:61. Telford WG, Frolova EG (2004). Discrimination of the Hoechst side population in mouse bone marrow with violet and near-ultraviolet laser diodes. Cytometry 57A:45. REVIEWS The November 23 issue of Semin. Liver Dis. is dedicated to reviews on hepatic stem cells. ARTICLES Cao YA, Wagers AJ, Beilhack A, Dusich J, Bachmann MH, Negrin RS, Weissman IL, Contag CH (2003). Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A. 2003 Dec 19 [Epub ahead of print] Cobas, M., Wilson, A., Ernst, B., Mancini, S. J. C., MacDonald, H. R., Kemler, R., and Radtke, F. (2004). {beta}-Catenin Is Dispensable for Hematopoiesis and Lymphopoiesis. J Exp Med, jem.20031615. Gregg C, Weiss S (2003). Generation of functional radial glial cells by embryonic and adult forebrain neural stem cells
January 6, 2004
REVIEW Unwin RD, Gaskell SJ, Evans CA, Whetton AD (2003). The potential for proteomic definition of stem cell populations. Exp Hematol 31:1147. METHODS Tang FC, Meng GL, Yang HB, Li CJ, Shi Y, Ding MX, Shang KG, Zhang B, Xue YF (2004). Stable Suppression of Gene Expression in Murine Embryonic Stem Cells by RNAi directed from DNA Vector-Based Short Hairpin RNA. Stem Cells 22:93. Vallier L, Rugg-Gunn PJ, Bouhon IA, Andersson FK, Sadler AJ, Pedersen RA (2004). Enhancing and diminishing gene function in human embryonic stem cells. Stem Cells 22:2. ARTICLES Bailey AS, Jiang S, Afentoulis M, Baumann CI, Schroeder DA, Olson SB, Wong MH, Fleming WH (2004). Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells. Blood 103:13. Chandran S, Kato H, Gerreli D, Compston A, Svendsen CN, Allen ND (2003). FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway. Development 130:6599. Gilboa L, Forbes A, Tazuke SI, Fuller MT, Lehmann R (2003). Germ line stem cell differentiation in Drosophila requires gap junctions and proceeds via an intermediate state. Development 130:6625. Lassalle B, Bastos H, Louis JP, Riou L, Testart J, Dutrillaux B, Fouchet P, Allemand I (2004). `Side Population' cells in adult mouse testis express Bcrp1 gene and are enriched in spermatogonia and germinal stem cells. Development 131: 479. Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T, Aiba K, Akutsu H, Sharova L, Tanaka TS, Kimber WL, Yoshikawa T, Jaradat SA, Pantano S, Nagaraja R, Boheler KR, Taub D, Hodes RJ, Longo DL, Schlessinger D, Keller J, Klotz E, Kelsoe G, Umezawa A, Vescovi AL, Rossant J, Kunath T, Hogan BL, Curci A, D'Urso M, Kelso J, Hide W, Ko MS (2003). Transcriptome Analysis of Mouse Stem Cells and Early Embryos. PLoS Biol 1:E74. Uchida N, Dykstra B, Lyons KJ, Leung FY, Eaves CJ (2003). Different in vivo repopulating activities of purified hematopoietic stem cells before and after being stimulated to divide in vitro with the same kinetics. Exp Hematol 31:1338. Traver D, Paw BH, Poss KD, Penberthy WT, Lin S, Zon LI (2003). Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol 4:1238. Watabe T, Nishihara A, Mishima K, Yamashita J, Shimizu K, Miyazawa K, Nishikawa S, Miyazono K (2003). TGF-{beta} receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells. J Cell Biol 163:1303. Xiao C, Shim JH, Kluppel M, Zhang SS, Dong C, Flavell RA, Fu XY, Wrana JL, Hogan BL, Ghosh S (2003). Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. Genes Dev 17:2933.
2003
December 23, 2003
PAPER OF THE MONTH REVIEW Ginis I, Rao MS (2003). Toward cell replacement therapy: promises and caveats. ARTICLES Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, Mann M (2003). Proteomic characterization of the human centrosome by protein correlation profiling. Nature 426:570. Easterday MC, Dougherty JD, Jackson RL, Ou J, Nakano I, Paucar AA, Roobini B, Dianati M, Irvin DK, Weissman IL, Terskikh AV, Geschwind DH, Kornblum HI Gilboa L, Forbes A, Tazuke SI, Fuller MT, Lehmann R (2003). Germ line stem cell differentiation in Drosophila requires gap junctions and proceeds via an intermediate state. Development 130:6625. Gu Y, Filippi MD, Cancelas JA, Siefring JE, Williams EP, Jasti AC, Harris CE, Lee AW, Prabhakar R, Atkinson SJ, Kwiatkowski DJ, Williams DA (2003).Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Science 302:445. Li TS, Hayashi M, Liu ZL, Ito H, Mikamo A, Furutani A, Matsuzaki M, Hamano K (2003). Low angiogenic potency induced by the implantation of ex vivo expanded CD117-positive stem cells. Am J Physiol Heart Circ Physiol. 2003 Dec 4 [Epub ahead of print] Norol F, Merlet P, Isnard R, Sebilion P, Bonnet N, Cailliot C, Carrion C, Ribeiro M, Charlotte F, Pradeau P, Mayol JF, Peinnequin A, Drouet M, Safsafi K, Vernant JP, Herodin F (2003). Influence of mobilized stem cells on myocardial infarct repair in a nonhuman primate model. Blood 102: 4361-4368 Pochampally RR, Smith JR, Ylostalo J, Prockop DJ (2003). Serum deprivation of human marrow stromal cells (hMSCs) selects for a sub-population of early progenitor cells with enhanced expression of Oct-4 and other embryonic genes. Blood published 20 November 2003, 10.1182/blood-2003-06-196 Sharov AA, Piao Y, Matoba R et al. (2003). Transcriptome analysis of mouse stem cells and early embryos. PLoS Biology December 22. PDF Shmelkov SV, Jun L, St. Clair R, McGarrigle D, Derderian CA, Usenko JK, Costa C, Zhang F, Guo X, Rafii S (2003). Alternative promoters regulate transcription of the gene encoding stem cell surface protein AC133. Blood published 20 November 2003, 10.1182/blood-2003-06-1881 BOOKS A collection of essays reviewing the principal arguments for and against stem cell research:
December 9, 2003
Daley GQ, Goodell MA, Snyder EY (2003). Realistic prospects for stem cell therapeutics. Hematology (Am Soc Hematol Educ Program). 2003:398. ARTICLES Camargo FD, Green R, Capetenaki Y, Jackson KA, Goodell MA (2003). Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates. Nat Med. 2003 Nov 16 [Epub ahead of print] Corbel SY, Lee A, Yi L, Duenas J, Brazelton TR, Blau HM, Rossi FM (2003). Contribution of hematopoietic stem cells to skeletal muscle. Nat Med. 2003 Nov 16 [Epub ahead of print] Vitry S, Bertrand JY, Cumano A, Dubois-Dalcq M (2003). Primordial hematopoietic stem cells generate microglia but not myelin-forming cells in a neural environment. J Neurosci 23:10724. Weimann JM, Johansson CB, Trejo A, Blau HM (2003). Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant. Nat Cell Biol 5:959. Wikramanayake AH, Hong M, Lee PN, Pang K, Byrum CA, Bince JM, Xu R, Martindale MQ (2003). An ancient role for nuclear beta-catenin in the evolution of axial polarity and germ layer segregation. Nature 426:446.
November 25, 2003
REVIEWS IMMUNOLOGICAL REVIEWS, VOLUME 196, PAGES 5-265: METHODS Frank AC, Meyers KA, Welsh IC, O'Brien TP (2003). Development of an enhanced GFP-based dual-color reporter to facilitate genetic screens for the recovery of mutations in mice. Proc Natl Acad Sci U S A. 2003 Nov 13 [Epub ahead of print] Pollitt SK, Pallos J, Shao J, Desai UA, Ma AA, Thompson LM, Marsh JL, Diamond MI (2003). A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor. Neuron 40:685. ARTICLES Cairns LA, Moroni E, Levantini E, Giorgetti A, Klinger FG, Ronzoni S, Tatangelo L, Tiveron C, De Felici M, Dolci S, Magli MC, Giglioni B, Ottolenghi S (2003). Kit regulatory elements required for expression in developing hematopoietic and germ cell lineages. Blood 102:3954. Dorsam ST, Ferrell CM, Dorsam GP, Derynck MK, Vijapurkar U, Khodabakhsh D, Pau B, Bernstein H, Haqq CM, Largman C, Lawrence HJ (2003). The transcriptome of the leukemogenic homeoprotein HOXA9 in human hematopoietic cells. Blood. 2003 Nov 6 [Epub ahead of print] Ye M, Iwasaki H, Laiosa CV, Stadtfeld M, Xie H, Heck S, Clausen B, Akashi K, Graf T (2003). Hematopoietic Stem Cells Expressing the Myeloid Lysozyme Gene Retain Long-Term, Multilineage Repopulation Potential. Immunity 19:689.
November 11, 2003
General Interest: Marshall D, Bagley J, Le P, Hogquist K, Cyr S, Von Schild E, Pykett M, Rosenzweig M (2003). T cell generation including positive and negative selection ex vivo in a three-dimensional matrix. J Hematother Stem Cell Res 12:565. Articles: Amsellem S, Pflumio F, Bardinet D, Izac B, Charneau P, Romeo PH, Dubart-Kupperschmitt A, Fichelson S (2003). Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein. Nat Med 9: 1423. Krosl J, Austin P, Beslu N, Kroon E, Humphries RK, Sauvageau G (2003). In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat Med 9: 1428. Gabay L, Lowell S, Rubin LL, Anderson DJ (2003). Deregulation of Dorsoventral Patterning by FGF Confers Trilineage Differentiation Capacity on CNS Stem Cells In Vitro. Neuron 40:485 Legg J, Jensen UB, Broad S, Leigh I, Watt FM (2003). Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis. Development 130: p. 6049. Sperger JM, Chen X, Draper JS, Antosiewicz JE, Chon CH, Jones SB, Brooks JD, Andrews PW, Brown PO, Thomson JA (2003). Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors. Proc Natl Acad Sci USA published 31 October 2003, 10.1073/pnas.2235735100 Taylor RW, Barron MJ, Borthwick GM, Gospel A, Chinnery PF, Samuels DC, Taylor GA, Plusa SM, Needham SJ, Greaves LC, Kirkwood TBL, Turnbull DM (2003). Mitochondrial DNA mutations in human colonic crypt stem cells. J Clin Invest 112: 1351. Ying Q-L, Nichols J, Chambers I, Smith A (2003). BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3. Cell 115:281
October 28, 2003
METHODS Comments on the “Stemness” and the transcriptional profiling of stem cells, in Science 302, pages 393b-d: Evsikov AV, Solter D. Comment on " 'Stemness': transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature". Levenberg S, Huang NF, Lavik E, Rogers AB, Itskovitz-Eldor J, Langer R (2003). Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. Murphy GJ, Gottgens B, Vegiopoulos A, Sanchez MJ, ;Leavitt AD, Watson SP, Green AR, Frampton J (2003). Manipulation of mouse hematopoietic progenitors by specific retroviral infection. J Biol Chem 278: 43556. REVIEWS Donovan PJ, de Miguel MP (2003). Turning germ cells into stem cells. pp 463-71. Ema H, Nakauchi H (2003). Self-renewal and lineage restriction of hematopoietic stem cells. pp 508-12. Le Douarin NM, Dupin E (2003). Multipotentiality of the neural crest. pp 529-36. Cossu G, Bianco P (2003). Mesoangioblasts - vascular progenitors for extravascular mesodermal tissues. pp 537-42. Doetsch F (2003). A niche for adult neural stem cells. pp 543-50 ARTICLES On stem cell niches Lemischka IR, Moore KA (2003). Stem cells: Interactive niches. Nature 425:778. Zhang J, Niu C, Ye L, Huang H, He X, Tong WG, Ross J, Haug J, Johnson T, Feng JQ, Harris S, Wiedemann LM, Mishina Y, Li L (2003). Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425:836. Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, Martin RP, Schipani E, Divieti P, Bringhurst FR, Milner LA, Kronenberg HM, Scadden DT (2003). Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425:841. General Chen D, McKearin D (2003). Dpp Signaling Silences bam Transcription Directly to Establish Asymmetric Divisions of Germline Stem Cells. Curr Biol 13:1786. Kaufman DS, Lewis RL, Hanson ET, Auerbach R, Plendl J, Thomson JA (2003). Functional endothelial cells derived from rhesus monkey embryonic stem cells. Blood. 2003 Oct 16 [Epub ahead of print] Le Blanc K, Tammik C, Rosendahl K, Zetterberg E, Ringden O (2003). HLA expression and immunologic propertiesof differentiated and undifferentiated mesenchymal stem cells. Exp Hematol 31:890. Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ (2003). Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003 Oct 22 [Epub ahead of print]
October 14, 2003
GENERAL INTEREST Bernstein E, Kim SY, Carmell MA, Murchison EP, Alcorn H, Li MZ, Mills AA, Elledge SJ, Anderson KV, Hannon GJ (2003). Dicer is essential for mouse development. Nat Genet. 2003 Oct 5 [Epub ahead of print] Alvarez-Dolado M, Pardal R, Garcia-Verdugo JM, Fike JR, Lee HO, Pfeffer K, Lois C, Morrison SJ, Alvarez-Buylla A (2003). Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature. 2003 Oct 12 [Epub ahead of print] REVIEWS Laslett AL, Filipczyk AA, Pera MF (2003). Characterization and culture of human embryonic stem cells. Trends Cardiovasc Med. 2003 Oct;13(7):295 ARTICLES Barberi T, Klivenyi P, Calingasan NY, Lee H, Kawamata H, Loonam K, Perrier AL, Bruses J, Rubio ME, Topf N, Tabar V, Harrison NL, Beal MF, Moore MA, Studer L (2003). Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol 21:1200. Li H, Liu H, Heller S (2003). Pluripotent stem cells from the adult mouse inner ear. Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, Dirks PB (2003). Identification of a Cancer Stem Cell in Human Brain Tumors. Cancer Res 63:5821. Xu P, Yoshioka K, Yoshimura D, Tominaga Y, Nishioka T, Ito M, Nakabeppu Y (2003). Zenzmaier C, Kollroser M, Gesslbauer B, Jandrositz A, Preisegger KH, Kungl
September 30, 2003
BOOKS HANDBOOK OF CELL SIGNALING (Three-volume set). GENERAL INTEREST Davidson AJ, Ernst P, Wang Y, Dekens MP, Kingsley PD, Palis J, Korsmeyer SJ, Daley GQ, Zon LI (2003). cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes. Nature 425:300. O'Connor-Giles KM, Skeath JB (2003). Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila. Dev Cell 5:231. Tsuda M, Sasaoka Y, Kiso M, Abe K, Haraguchi S, Kobayashi S, Saga Y (2003). Conserved role of nanos proteins in germ cell development. Science 301 :1239. ARTICLES Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K, Leri A, Kajstura J, Nadal-Ginard B, Anversa P (2003). Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114:763. Toyooka Y, Tsunekawa N, Akasu R, Noce T (2003). Embryonic stem cells can form germ cells in vitro. Proc Natl Acad Sci U S A. 2003 Sep 22 [Epub ahead of print] Vrana KE, Hipp JD, Goss AM, McCool BA, Riddle DR, Walker SJ, Wettstein PJ, Studer LP, Tabar V, Cunniff K, Chapman K, Vilner L, West MD, Grant KA, Cibelli JB (2003). Nonhuman primate parthenogenetic stem cells. Proc Natl Acad Sci U S A. 2003 Sep 22 [Epub ahead of print]
September 16, 2003
General interest Marx J (2003). Cancer research. Mutant stem cells may seed cancer. Science 301:1308. Park T, Yi SG, Kang SH, Lee S, Lee YS, Simon R (2003). Evaluation of Normalization Methods for Microarray Data. BMC Bioinformatics. 2003 Sep 2 [Epub ahead of print] Full text online. Special Review Issue of Philosphical Transactions: Biological Sciences, published by the Royal Society, UK. Methods Lee HS, Crane GG, Merok JR, Tunstead JR, Hatch NL, Panchalingam K, Powers MJ, Griffith LG, Sherley JL (2003). Clonal expansion of adult rat hepatic stem cell lines by suppression of asymmetric cell kinetics (SACK). Biotechnol Bioeng 83:760. Luo Y, Cai J, Ginis I, Sun Y, Lee S, Yu SX, Hoke A, Rao M (2003). Designing, Testing, and Validating a Focused Stem Cell Microarray for Characterization of Neural Stem Cells and Progenitor Cells. Stem Cells 21: 575. Richards M, Tan S, Fong CY, Biswas A, Chan WK, Bongso A (2003). Comparative Evaluation of Various Human Feeders for Prolonged Undifferentiated Growth of Human Embryonic Stem Cells.
Bailey AS, Jiang S, Afentoulis M, Baumann CI, Schroeder DA, Olson SB, Wong Kaufman CK, Zhou P, Pasolli HA, Rendl M, Bolotin D, Lim KC, Dai X, Alegre ML, Fuchs E (2003). GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev 17:2108. McCroskery S, Thomas M, Maxwell L, Sharma M, Kambadur R (2003). Myostatin negatively regulates satellite cell activation and self-renewal. J Cell Biol. 2003 Sep 8 [Epub ahead of print] Machold R, Hayashi S, Rutlin M, Muzumdar MD, Nery S, Corbin JG, Gritli-Linde A, Dellovade T, Porter JA, Rubin LL, Dudek H, McMahon AP, Fishell G (2003). Sonic Hedgehog Is Required for Progenitor Cell Maintenance in Telencephalic Stem Cell Niches. Neuron 39:937. O'Connor-Giles KM, Skeath JB (2003). Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila. Dev Cell 5:231. Wang Z, Cohen K, Shao Y, Mole P, Dombkowski D, Scadden DT (2003). Ephrin receptor, EphB4, regulates ES cell differentiation of primitive mammalian hemangioblasts, blood, cardiomyocytes, and blood vessels. Blood. 2003 Sep 4 [Epub ahead of print] Yamashita YM, Jones DL, Fuller MT (2003). Orientation of Asymmetric Stem Cell Division by the APC Tumor Suppressor and Centrosome. Science 301:1547. Zhang Z, Cotta CV, Stephan RP, deGuzman CG, Klug CA (2003). Enforced expression of EBF in hematopoietic stem cells restricts lymphopoiesis to the B cell lineage. EMBO J. 22:4759.
September 2, 2003
General Interest “Human Cloning and Human Dignity: An Ethical Inquiry”. Released by the President’s Council on Bioethics is available full text (179 pages) at: http://www.bioethics.gov/reports/cloningreport/fullreport-print.html Rider TH, Petrovick MS, Nargi FE, Harper JD, Schwoebel ED, Mathews RH, Blanchard DJ, Bortolin LT, Young AM, Chen J, Hollis MA (2003). A B cell-based sensor for rapid identification of pathogens. Science 301:213. The authors describe an ingenious detection assay for pathogens, and potentially any defined epitope, such as in medical diagnostic tests, biowarfare and food- and water-quality monitoring. By establishing B cell lines that express stably jellyfish aequorin, a reporter for Ca2+ mobilization, and antibody receptors specific for the epitope in question, they can monitor within several minutes only, and with high sensitivity, activation of the B cells and thus achieve detection of the epitope. The cells can be stored at RT for 2 days, refrigerated for 2 weeks, or even frozen down. Grewal SI, Moazed D (2003).Heterochromatin and epigenetic control of gene expression. Science 301:798. Broad but concise review about gene regulation and heritable gene silencing, through heterochromatin, and the roles of repetitive DNA sequences, non-coding RNAs, dsRNA, shRNAs and RNAi pathway therein. Articles Aubert J, Stavridis MP, Tweedie S, O'Reilly M, Vierlinger K, Li M, Ghazal P, Pratt T, Mason JO, Roy D, Smith A (2003). Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice. Proc Natl Acad Sci U S A. 2003 Aug 15 [Epub ahead of print] Ara T, Tokoyoda K, Sugiyama T, Egawa T, Kawabata K, Nagasawa T (2003). Long-Term Hematopoietic Stem Cells Require Stromal Cell-Derived Factor-1 for Colonizing Bone Marrow during Ontogeny. Immunity 19:257. Byrne JA, Simonsson S, Western PS, Gurdon JB (2003). Nuclei of adult mammalian somatic cells are directly reprogrammed to oct-4 stem cell gene expression by amphibian oocytes. Curr Biol 13:1206. Bieberich E, MacKinnon S, Silva J, Noggle S, Condie BG (2003). Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide. J Cell Biol 162:469. D'Amour KA, Gage FH (2003). Genetic and functional differences between multipotent neural and pluripotent embryonic stem cells. Proc Natl Acad Sci U S A. 2003 Aug 15 [Epub ahead of print] Gurdon JB, Byrne JA, Simonsson S (2003). Nuclear reprogramming and stem cell creation. Proc Natl Acad Sci U S A. 2003 Aug 14 [Epub ahead of print] Kaufman CK, Zhou P, Pasolli HA, Rendl M, Bolotin D, Lim KC, Dai X, Alegre ML, Fuchs E (2003). GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev. 2003 Aug 15 [Epub ahead of print] Kyba M, Perlingeiro RC, Hoover RR, Lu CW, Pierce J, Daley GQ (2003). Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5. Proc Natl Acad Sci U S A. 2003 Aug 20 [Epub ahead of print] Levasseur DN, Ryan TM, Pawlik KM, Townes TM (2003). Correction of a mouse model of sickle cell disease: lentiviral/anti-sickling {beta}-globin gene transduction of unmobilized, purified hematopoietic stem cells. Blood. 2003 Aug 21 [Epub ahead of print] Oliveira DM, Goodell MA (2003). Transient RNA interference in hematopoietic progenitors with functional consequences. Genesis 36:203. Sato N, Sanjuan IM, Heke M, Uchida M, Naef F, Brivanlou AH (2003). Molecular signature of human embryonic stem cells and its comparison with the mouse. Dev Biol 260:404. Verstegen MM, Wognum AW, Wagemaker G (2003). Thrombopoietin is a major limiting factor for selective outgrowth of human umbilical cord blood cells in non-obese diabetic/severe combined immunodeficient recipient mice. Br J Haematol 122:837.
August 19, 2003
General Interest Galli C, Lagutina I, Crotti G, Clooeoni S, Turini P, Ponderato N, Duchi R, lazar G (2003). A cloned Horse is born to its dam twin. Nature 424:635. Kaspar BK, Llado J, Sherkat N, Rothstein JD, Gage FH. Zhu J, Shendure J, Mitra RD, Church GM (2003). Single molecule profiling of alternative pre-mRNA splicing. Science 301:836.
Cairns LA, Moroni E, Levantini E, Giorgetti A, Klinger FG, Ronzoni S, Hristo B. Houbaviy, Michael F. Murray, Sharp A (2003).Embryonic Stem Cell-Specific MicroRNAs. Dev Cell 5:351. Horn PA, Thomasson BM, Wood BL, Andrews RG, Morris JC, Kiem HP (2003). Distinct hematopoietic stem/progenitor cell populations are responsible for repopulating NOD/SCID mice versus nonhuman primates. Blood. 2003 Jun 19 [Epub ahead of print]. Mangi AA, Noiseux N, Kong D, He H, Rezvani M, Ingwall JS, Dzau VJ (2003). Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infracted hearts. Nature Medicine, AOP doi: 10.1038/nm912, (2003). Migishima F, Oikawa A, Kondo S, Ema H, Morita Y, Nakauchi H, Yokoyama M, Song SY, Nishijima M, Okabe M, Shinohara N (2003). Full reconstitution of hematopoietic system by murine umbilical cord blood. Transplantation 75:1820.
August 5, 2003
General Interest Lysaght MJ, Hazlehurst AL (2003). Private sector development of stem cell technology and therapeutic cloning. Tissue Eng 9:555. Rimmer M (2003). The attack of the clones: patent law and stem cell research. J Law Med 10:488. Reviews Pevny L, Rao MS (2003). The stem-cell menagerie. Trends Neurosci 26:351. Rhind SM, King TJ, Harkness LM, Bellamy C, Wallace W, DeSousa P, Wilmut I (2003). Cloned lambs-lessons from pathology. Nature Biotechnol 21: 744. Methods Articles Emambokus NR, Frampton J (2003). The glycoprotein IIb molecule is expressed on early murine hematopoietic progenitors and regulates their numbers in sites of hematopoiesis. Immunity 19:33. Helgason CD, Antonchuk J, Bodner C, Humphries RK (2003). Homeostasis and regeneration of the hematopoietic stem cell pool is altered in SHIP-deficient mice. Blood. Jul 10 [Epub ahead of print]. Hess D, Li L, Martin M, Sakano S, Hill D, Strutt B, Thyssen S, Gray DA, Bhatia M (2003). Bone marrow-derived stem cells initiate pancreatic regeneration. Nat Biotechnol 21:763. Horn PA, Thomasson BM, Wood BL, Andrews RG, Morris JC, Kiem HP (2003). Distinct hematopoietic stem/progenitor cell populations are responsible for repopulating NOD/SCID mice versus nonhuman primates. Blood Jun 19 [Epub ahead of print]. Latinkic BV, Kotecha S, Mohun TJ (2003). Induction of cardiomyocytes by GATA4 in Xenopus ectodermal explants. Development 130:3865. Mogi M, Yang J, Lambert JF, Colvin GA, Shiojima I, Skurk C, Summer R, Fine A, Quesenberry PJ, Walsh K (2003). Akt-signaling regulates side-population cell phenotype via Bcrp1 translocation. J Biol Chem Jul 8 [Epub ahead of print]. Sampaolesi M, Torrente Y, Innocenzi A, Tonlorenzi R, D'Antona G, Pellegrino MA, Barresi R, Bresolin N, De Angelis MG, Campbell KP, Bottinelli R, Cossu G (2003). Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts. Science 301:487.
July 24, 2003
Rafii S and Lyden D. (2003). Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med. 9:702-12. Review. M. Sampaolesi, Y. Torrente, A. Innocenzi, R. Tonlorenzi, G. D'Antona, M. A. Pellegrino, R. Barresi, N. Bresolin, M. G. Cusella De Angelis, K. P. Campbell, R. Bottinelli, and G. Cossu (2003). Cell Therapy of Error! Unknown switch argument.-Sarcoglycan Null Dystrophic Mice Through Intra-Arterial Delivery of Mesoangioblasts. Science online July 10. Suzuki A, Iwama A, Miyashita H, Nakauchi H, Taniguchi H (2003). Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells.
July 1, 2003
Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M, Yamanaka S. "The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells." Cell 113:631-42. Chambers I, Colby D, Robertson M, Nichols J, Lee S, Tweedie S, Smith A. (2003). "Functional expression cloning of nanog, a pluripotency sustaining factor in embryonic stem cells." Hubner K, Fuhrmann G, Christenson LK, Kehler J, Reinbold R, De La Fuente R,
2002
November 1, 2002
July Issue of Journal of Pathology, vol 197, with reviews on prostatic, neural, lung epithelial, pancreatic, hepatic, gastrointestinal, epidermal, cardiac, muscle, hematopoietic, and embryonic stem cells. Burdon T, Smith A, Savatier P (2002)."Signalling, cell cycle and pluripotency in embryonic stem cells."Trends Cell Biol 12:432. Bradley JA, Bolton EM, Pedersen RA (2002). "Stem cell medicine encounters the immune system." Nat Rev Immunol. 2:859. Daley G (2002)."Prospects for stem cell therapeutics: myths and medicines." Curr Opin Genet Dev 12:607. Eiges R, Benvenisty N (2002)."A molecular view on pluripotent stem cells." FEBS Lett 529:135. Frisen J (2002)."Stem cell plasticity?" Neuron 35:415. Noel D, Djouad F, Jorgense C (2002). "Regenerative medicine through mesenchymal stem cells for bone and cartilage repair." Curr Opin Investig Drugs 3:1000. Presnell S, Petersen B, Heidaran M (2002)."Stem cells in adult tissues." Semin Cell Dev Biol 13:369. Tisdale JF, Dunbar CE (2002)."Plasticity and hematopoiesis: Circe's transforming potion?" Curr Opin Hematol 9:268. Weissman IL (2002). "The road ended up at stem cells." Immunol Rev. 185:159. Wilmut I, Beaujean N, De Sousa PA, Dinnyes A, King TJ, Paterson LA, Wells DN, Young LE (2002)."Somatic cell nuclear transfer." Nature 419:583.
November 1, 2002
Asano T, Hanazono Y, Ueda Y, Muramatsu S, Kume A, Suemori H, Suzuki Y, Kondo Y, Harii K, Hasegawa M, Nakatsuji N, Ozawa K (2002)."Highly efficient gene transfer into primate embryonic stem cells with a simian lentivirus vector." Mol Ther 6:162. Falk A, Holmstrom N, Carlen M, Cassidy R, Lundberg C, Frisen J (2002)."Gene delivery to adult neural stem cells." Exp Cell Res 279:34. Fijnvandraat AC, De Boer PA, Deprez RH, Moorman AF (2002)."Non-radioactive in situ detection of mRNA in ES cell-derived cardiomyocytes and in the developing heart." Microsc Res Tech 58:387. Levsky JM, Shenoy SM, Pezo RC, Singer RH. (2002). "Single-cell gene expression profiling." Science, 297:836. Murphy CL, Polak JM (2002)."Differentiating Embryonic Stem Cells: GAPDH, But Neither HPRT Nor beta-Tubulin Is Suitable as an Internal Standard for Measuring RNA Levels." Tissue Eng 8:551. Nagano M, Watson DJ, Ryu BY, Wolfe JH, Brinster RL (2002)." Lentiviral vector transduction of male germ line stem cells in mice." FEBS Lett 524:111. Pedersen RA (2002)."Feeding hungry stem cells." Nat Biotechnol 20:882-3.
November 1, 2002
Castro, RF, Jackson KA, Goodell MA, Robertson CS, Liu H, Shine HD (2002)." Failure of bone marrow cells to transdifferentiate into neural cells in vivo." Science 297:1299. Drukker M, Katz G, Urbach A, Schuldiner M, Markel G, Itskovitz-Eldor J, Reubinoff B, Mandelboim O, Benvenisty N (2002)."Characterization of the expression of MHC proteins in human embryonic stem cells." Proc Natl Acad Sci U S A 99:9864. Hackney JA, Charbord P, Brunk BP, Stoeckert CJ, Lemischka IR, Moore KA (2002)."A molecular profile of a hematopoietic stem cell niche." Proc Natl Acad Sci U S A 99:13061. Hanna LA, Foreman RK, Tarasenko IA, Kessler DS, Labosky PA (2002)."Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo." Genes Dev 20:2650. Heyworth C, Pearson S, May G, Enver T (2002)."Transcription factor-mediated lineage switching reveals plasticity in primary committed progenitor cells." EMBO J. 21:3770. Humpherys D, Eggan K, Akutsu H, Friedman A, Hochedlinger K, Yanagimachi R, Lander ES, Golub TR, Jaenisch R (2002)."Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei." Proc Natl Acad Sci U S A 99:12889. Ivanova NB, Dimos JT, Schaniel C, Hackney JA, Moore KA, Lemischka IR (2002). Jirmanova L, Afanassieff M, Gobert-Gosse S, Markossian S, Savatier P (2002)." Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells." Kim JH, Auerbach JM, Rodriguez-Gomez JA, Velasco I, Gavin D, Lumelsky N, Lee SH, Nguyen J, Sanchez-Pernaute R, Bankiewicz K, McKay R. (2002) "Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease." Nature, 418:50. Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA (2002). "Stemness": transcriptional profiling of embryonic and adult stem cells." Science 298:597. Schmidt M, Zickler P, Hoffmann G, Haas S, Wissler M, Muessig A, Tisdale JF, Kuramoto K, Andrews RG, Wu T, Kiem HP, Dunbar CE, von Kalle C (2002)."Polyclonal long-term repopulating stem cell clones in a primate model." Blood. 100:2737. Tsai EJ, Malech HL, Kirby MR, Hsu AP, Seidel NE, Porada CD, Zanjani ED, Bodine DM, Puck JM (2002)."Retroviral transduction of IL2RG into CD34(+) cells from X-linked severe combined immunodeficiency patients permits human T- and B-cell development in sheep chimeras." Blood100:72. Wagers AJ, Sherwood RI, Christensen JL, Weissman IL (2002)."Little evidence for developmental plasticity of adult hematopoietic stem cells." Science 297:2256. Xu C, Police S, Rao N, Carpenter MK (2002). Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells."Circ Res 91:501.
August 1, 2002
Research The Stem Cell Plasticity Controversy Wumser, A.E. and F. H. Gage. 2002. Stem cells: cell fusion causes confusion. Nature, 416:485-7. A "News and Views" comment on two Nature articles: Terada, N, T. Hamazaki, M. Oka, M. Hoki, D. M. Mastalerz, Y. Nakano, E. M. Meyer, L. Morel, B. E. Petersen, and E.W. Scott. 2002. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature, 416:542-5. In this article, the authors demonstrate that by coculturing bone marrow cells from female mice transgenic for the GFP and puromycin gene with male embryonic stem cells, they obtained a fusion product, displaying embryonic stem cell phenotype and expressing embryonic cell markers. These cells expressed GFP and puromycin resistance, were over-diploid, and were able to differentiate into cardiac myocytes, neuron-like cells and were able to produce teratomas in NOD/SCID mice. Ying, Q. L., J. Nichols, E. P. Evans, and A.G. Smith. 2002. Changing potency by spontaneous fusion. Nature, 416:545-8. With a slightly different approach, the authors demonstrate fusion between forebrain cells of transgenic fetuses with ES cells. The fusion product had full ES cell pluripotent character, including multilineage contribution to chimeras. They also succeeded in establishing fusion products between ES cells and adult brain cells (8-week-old mice). Other Articles of Interest Jiang, Y., B. N. Jahagirdar, R. L. Reinhardt, R. E. Schwartz, C. D. Keene, X. R. Ortiz-Gonzalez, M. Reyes, T. Lenvik, T. Lund, M. Blackstad, J. S. Du, , A. Lisberg, W. C. Low, D. A. Largaespada, and C. M. Verfaillie. 2002. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature, 418:41-9. Toma, J. G., M. Akhavan, K. J. Fernandes, F. Barnabe-Heider, A. Sadikot, D. R. Kaplan, F. D. Miller. 2001. Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nat Cell Biol, 3:778-84. Sata, M., A. Saiura, A. Kunisato, A. Tojo, S.Okada, T. Tokuhisa, H. Hirai, M. Makuuchi, Y. Hirata, and R. Nagai. 2002. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nature Medicine, 8:403-9. Morshead, C. M., P. Beneviste, N. N. Iscove, and D. van der Kooy. 2002. Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations. Nature Medicine, 8:268-73. Reviews on Plasticity Gardner, R. L. 2002. Stem cells: potency, plasticity and public perception. J Anat, 200:277-82. Orkin, S. H., and L. I. Zon. 2002. Hematopoiesis and stem cells: plasticity versus developmental heterogeneity. Nat Immunol, 3:323-8. Tsai, R.Y., R. Kittappa, and R. D. McKay. 2002. Plasticity, niches, and the use of stem cells. Dev Cell, 2:707-12. Krause, D.S. 2002. Plasticity of marrow-derived stem cells. Gene Ther, 9:754-8. Peterson, D. A. 2002. Stem cells in brain plasticity and repair. Curr Opin Pharmacol, 2:34-42. Gritti, A., A. L. Vescovi, R. Galli 2002. Adult neural stem cells: plasticity and developmental potential. J Physiol Paris, 96:81-90. Special issue on Stem Cell Plasticity It will be available online after August 9 at http://www.elsevier.com/locate/exphemonline And for 112 pages of light reading at the end of the day... On the Web List of the 13 institutions that provide together 78 NIH-approved human embryonic stem cell lines, including e-mail addresses to request them. U.S. Government National Institutes of Health Stem Cell Information Page
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